C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
530/15.14
C07K 15/14 (1985.01)
Patent
CA 1213885
PREPARATION OF ANTITUMOR AGENT FROM SHELLFISH ABSTRACT OF THE DISCLOSURE A new antitumor agent is provided which consists essentially of water-soluble, macromolecular glycoprotein substances having a range of molecular weights within the limits of from 10,000 to 300,000 and which is prepared from shellfish or mollusc by taking up the liquid portion which comes from the cooking of raw shellfish in an aqueous solvent, typically water or a saline solution, or vapor of such solvent and which is to be discarded as waste, concentrating the liquid portion to a smaller volume or to dryness, dissolving the resulting concentrate or dry powder in an aqueous solvent and isolating the desired water-soluble, macromolecular glycoprotein substances therefrom. The isolation of the desired substances is preferably carried out by an ion-exchange chromatography with a basic anion-exchanger followed by a gel-filtration.
408930
Nakamichi Kazuya
Sasaki Takuma
Macrae & Co.
Maruzen Oil. Ltd.
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