Preparation of aromatic acetamides from aryl methyl ketones

Details Preparation of aromatic acetamides from aryl methyl ketones Preparation of aromatic acetamides from aryl methyl ketones

C - Chemistry, Metallurgy

07

C

C07C 231/10 (2006.01) C07C 233/11 (2006.01) C07C 235/34 (2006.01) C07C 237/20 (2006.01)

Patent

CA 2047130

ATC-0004 ABSTRACT OF THE DISCLOSURE A method is provided for preparing aromatic acetamides comprising reacting an aryl methyl ketone containing the same number of carbon atoms as the aromatic acetamide, with sulfur and ammonia under substantially anhydrous conditions. The method is particularly useful for the preparation of 4-hydroxyphenylacetamide from 4-hydroxyacetophenone.

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