Preparation of aromatic amides

Details Preparation of aromatic amides Preparation of aromatic amides

C - Chemistry, Metallurgy

07

D

260/292, 260/279

C07D 211/34 (2006.01) C07D 409/06 (2006.01)

Patent

CA 1082710

Abstract of the Disclosure Aromatic amides of the formula Image in which R is lower alkoxy or alkenoxy; R1 and R2 are each hydrogen, halogen, sulfonamido, amino, lower alkylamino, dialkylamino, lower alkyl sulfonyl, alkylsulfonamido or acylamino, R1 being in the 3- or 4- position of the aromatic ring R3 is hydrogen, lower alkyl or aryl; Ar is aryl, aroyl or mono- cyclic aromatic heterocyclic; x is 0 or 1; y is 2 or 3 and z is an integer from 1 to 6, and pharmaceutically acceptable salts thereof, are disclosed, as well as methods for their preparation The compounds (I) possess various activities useful in the treatment of gastrointestinal and cerebral mal- functions in mammals.

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