Preparation of biodegradeable microparticles containing a...

A - Human Necessities – 61 – K

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A61K 9/16 (2006.01) A61K 31/519 (2006.01) A61K 31/568 (2006.01) A61K 31/57 (2006.01) B01J 13/02 (2006.01)

Patent

CA 2474701

A process for preparing biodegradable microparticles comprising a biodegradable polymeric binder and a biologically active agent. A first phase, comprising the active agent and the polymer, and a second phase are pumped through a static mixer into a quench liquid to form microparticles containing the active agent. Preferably, a blend of at least two substantially non-toxic solvents, free of halogenated hydrocarbons, is used to dissolve or disperse the agent and dissolve the polymer.

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