Preparation of c-pyrazine-methylamines

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 241/16 (2006.01) C07D 401/06 (2006.01)

Patent

CA 2752826

A process for preparing a compound of formula (I) or a salt thereof: (I) wherein R1 is H or optionally substituted aryl or heteroaryl; comprising reacting 2,3- dichloropyrazine with a suitable diaryl imine followed by hydrolysis.

L'invention porte sur un procédé de préparation d'un composé de formule (I) ou d'un sel de celui-ci : (I), où R1 représente H ou un radical aryle ou hétéroaryle éventuellement substitué. Ce procédé comprend la réaction de 2,3-dichloropyrazine avec une diaryl imine appropriée, suivie d'une hydrolyse.

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