Preparation of clavulanic acid and its salts and esters

C - Chemistry – Metallurgy – 12 – P

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C12P 17/18 (2006.01) C07D 503/00 (2006.01)

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CA 1307223

ABSTRACT PREPARATION OF CLAVULANIC ACID AND ITS SALTS AND ESTERS At least part of the assimilable carbon source is added to the culture medium when producing clavulanic acid by fermentation with a producing micro-organism. The clavulanic acid is readily obtained in good yield and purity, preferably as an ester or salt in a form suited for formulation as pharmaceuticals.

494016

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