C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/54 (2006.01) A61K 31/4164 (2006.01) A61K 51/04 (2006.01) C07D 233/91 (2006.01)
Patent
CA 2379974
Novel 18F-fluorine compounds useful for non-invasive imaging techniques such as PET, for detecting tissue hypoxia, and methods for preparing them are disclosed. Novel intermediate compounds and methods for preparing them are also disclosed. Diagnostic kits useful in practicing the methods of claimed invention are also provided.
L'invention porte sur de nouveaux composés fluorés marqués [?18¿F], qui sont utiles dans des techniques d'imagerie non invasives, telles qu'une tomographie par émission de positrons (TEP) destinées à détecter une hypoxie tissulaire. L'invention concerne des méthodes de préparation desdits composés, ainsi que de nouveaux composés intermédiaires et des méthodes pour les préparer. Elle concerne en outre des trousses de diagnostic utiles pour la mise en oeuvre des méthodes de l'invention.
Dolbier William R.
Kachur Alexander V.
Koch Cameron J.
Li An-Rong
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
The Trustees Of The University Of Pennsylvania
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