Preparation of delta-keto-esters

C - Chemistry – Metallurgy – 07 – C

Patent

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260/488, 260/479

C07C 69/716 (2006.01) C07C 67/313 (2006.01) C07C 67/347 (2006.01) C07C 69/66 (2006.01) C07C 69/74 (2006.01)

Patent

CA 1123005

ABSTRACT OF THE DISCLOSURE Delta-keto-esters such as 4-oxopentane-1-carboxylic acid methyl ester and the like, are prepared in the presence of a primary amine, a Schiff base, or both, by reacting a ketone having at least one hydrogen atom in the alpha position and an alpha-beta unsaturated carboxylic acid ester in the presence of an acid according to the disclosed invention.

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