Preparation of derivatives of fluorenes and fluoranthenes

Details Preparation of derivatives of fluorenes and fluoranthenes Preparation of derivatives of fluorenes and fluoranthenes

C - Chemistry, Metallurgy

07

D

260/242.01, 260/

C07D 487/16 (2006.01) C07D 471/04 (2006.01) C07D 471/14 (2006.01) C07D 471/16 (2006.01)

Patent

CA 1107729

A B S T R A C T Derivatives of fluorenes and fluoranthenes are provided, in the form of racemates or of enantiomers, of the formula (I) Image (I) in which n is 1 or 2, R1 is a hydrogen, chlorine or fluorine atom or a C1-C4 alkyl or C1-C4 alkoxy radical, R2 is a hydrogen atom or a C1-C4 alkyl, cyclopropyl, benzyl, chloro or fluorobenzyl, C1-C4 alkylbenzyl, C1-C4 alkoxy- benzyl, C1-C4 acyl, C1-C4 alkoxycarbonyl or C1-C4 alkyl- aminocarbonyl radical, R3 is a hydrogen atom or a C1-C4 alkyl radical, R4 is a hydrogen atom or a C1-C4 alkyl, C1-C4 acyl or benzoyl radical, and pharmaceutically acceptable acid addition salts thereof. They are therapeutically valuable as anti-anoxia and psychotropic agents.

332589

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