Preparation of diagnostic test strips containing tetrazolium...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/61 (2006.01) C12Q 1/54 (2006.01) C12Q 1/60 (2006.01) G01N 33/52 (2006.01)

Patent

CA 2122237

Disclosed is an improved procedure for the manu- facture of a diagnostic test device comprising a matrix having uniformly dispersed a tetrazolium salt and a reagent system designed to convert the tetrazolium to its colored formazan upon contacting the matrix with a fluid containing an analyte whose presence and/or concentration is being sought. The procedure involves applying the tetrazolium salt to the matrix from its solution in an organic solvent and, after drying, applying the reagent system to the matrix from its aqueous solution to which has been added hexanesulfonate as wetting agent.

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