Preparation of directly iodinated steroid hormones and...

Details Preparation of directly iodinated steroid hormones and... Preparation of directly iodinated steroid hormones and...

C - Chemistry, Metallurgy

07

J

260/7

C07J 1/00 (2006.01) A61K 51/04 (2006.01) C07J 5/00 (2006.01) G01N 33/74 (2006.01)

Patent

CA 1102305

PREPARATION OF DIRECTLY IODINATED STEROID HORMONES AND RELATED COMPOUNDS ABSTRACT OF THE DISCLOSURE: A process for the direct iodination of steroids and steroid hormones in the presence of hydrogen peroxide or chloramine-T is disclosed. The antigenicity and the specific receptor binding of directly iodinated estradiol 17-beta is iden- tical to tritiated estradiol 17-beta.

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