Preparation of halofluorobenzenes

C - Chemistry – Metallurgy – 07 – C

Patent

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260/653.6

C07C 17/20 (2006.01) C07C 25/13 (2006.01)

Patent

CA 2003918

ABSTRACT Chlorofluorobenzenes and difluorobenzenes are prepared by reacting a dichlorobenzene with an effective amount of KF or CsF, in a polar aprotic solvent, at an elevated temperature, and under substantially anhydrous conditions. The product can be removed as it is formed or the reaction may be run at the autogenous pressures generated by the reaction mixture in a sealed reactor. 37,135-F

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