Preparation of hydrochloride salts of tetrazole derivative

Details Preparation of hydrochloride salts of tetrazole derivative Preparation of hydrochloride salts of tetrazole derivative

C - Chemistry, Metallurgy

07

D

C07D 403/10 (2006.01) A61K 31/415 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2575254

The present invention relates to sesquihydrate hydrochloride salt of irbesartan and anhydrous hydrochloride salts of irbesartan. Irbesartan used as the starting material for the preparation of the described hydrochlorides of irbesartan can be in any form, e.g. it can be used when contained in a reaction solution, in crude form, in a filtrate containing several solvents, or in anhydrous or any solvated or hydrated form, in amorphous form or any known crystal form or in a mixture thereof.

La présente invention concerne un sel sesquihydrate chlorhydrate d'irbésartan ainsi que des sels de chlorhydrate anhydride d'irbésartan. L'irbésartan utilisé comme matière de départ dans la préparation des chlorhydrates d'irbésartan de l'invention peut se présenter sous n'importe quelle forme, par exemple elle peut être utilisée lorsqu'elle est contenue dans une solution de réaction, sous une forme brute, dans un filtrat contenant plusieurs solvants ou sous une forme anhydre ou n'importe quelle forme solvatée ou hydratée, sous une forme amorphe ou sous n'importe quelle forme cristalline connue ou bien en un mélange.

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