C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 1/00 (2006.01) C07C 29/48 (2006.01) C07C 35/32 (2006.01) C07C 35/36 (2006.01) C07C 35/52 (2006.01) C07C 43/196 (2006.01) C07C 62/32 (2006.01) C07C 69/757 (2006.01) C07C 215/44 (2006.01) C07C 233/23 (2006.01) C07C 247/14 (2006.01) C07C 255/47 (2006.01) C07C 323/17 (2006.01) C07D 209/30 (2006.01) C07D 221/04 (2006.01) C07F 9/28 (2006.01) C12P 7/22 (2006.01) C12P 7/42 (2006.01) C12P 9/00 (2006.01) C12P 11/00 (2006.01) C12P 13/00 (2006.01) C12P 17/00 (2006.01)
Patent
CA 2216248
A process for preparing a compound of formula (3) in which R2 is -H; which comprises the steps: (i) conversion of a compound of formula (1) into a compound of formula (2) using a dioxygenase enzyme; (ii) conversion of the compound of formula (2) into a compound of formula (3) wherein is -COR; and (iii) conversion of the compound of formula (3) in which R2 is -COR into a compound of formula (3) in which R2 is -H; wherein R2, a, b, c, d, Z, m and X are as defined in Claim 1. Also claimed are individual steps of the process and new compounds of formula (2).
L'invention se rapporte à un procédé de préparation d'un composé de la formule (3) dans laquelle R?2¿ représente -H, ce procédé comprenant les étapes suivantes: (i) conversion d'un composé de la formule (1) en un composé de la formule (2) à l'aide d'une enzyme dioxygénase; (ii) conversion du composé de la formule (2) en un composé de la formule (3) dans laquelle R?2¿ représente -COR; et (iii) conversion du composé de la formule (3) dans laquelle R?2¿ représente -COR en un composé de la formule (3) dans laquelle R?2¿ représente -H; et où R?2¿, a, b, c, d, Z, m et X sont tels que définis dans la revendication 1. Sont également revendiqués des étapes individuelles du procédé et des nouveaux composés de formule (2).
Blacker Andrew John
Bowers Nigel
Boyd Derek Raymond
Dalton Howard
Avecia Limited
Smart & Biggar
Zeneca Limited
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