Preparation of intermediates and the synthesis of...

Details Preparation of intermediates and the synthesis of... Preparation of intermediates and the synthesis of...

C - Chemistry, Metallurgy

07

D

260/292.5

C07D 211/44 (2006.01) C07D 211/46 (2006.01) C07D 498/04 (2006.01)

Patent

CA 2028909

A process for the preparation of N-(2-hydroxyethyl)- 2-hydroxymethyl-3,4,5-trihydroxypiperidines of the formula (see formula I), which comprises reacting a compound of the formula (see formula II) with glyoxal of the formula (see formula III) in a solvent to give the addition product (see formula IV) and reducing such addition product (II) with a hydrogen donor reducing agent to produce the intermediates of the formula (see formula I) and then the end product (I).

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