Preparation of intermediates in the synthesis of quinoline...

C - Chemistry – Metallurgy – 07 – D

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C07D 209/52 (2006.01)

Patent

CA 2131160

This invention relates to novel processes for preparing compounds of formulae (III) and (VII) wherein R and X defined as below. Compounds of the formulae (VII) are useful as intermediates in the syntheses of azabicyclo quinoline carboxylic acids having antibacterial activity. This invention also relates to certain novel intermediates in the syntheses such antibiotics.

Le présent brevet porte sur de nouveaux procédés pour la préparation de composés de formules (III) et (VII) dans lesquelles R et X sont définis comme ci-dessous. Les composés de formules (VII) sont utilisés comme intermédiaires dans la synthèse d'acides carboxyliques azabicyclo quinoline à activité antibactérienne. Le présent brevet porte aussi sur certains nouveaux intermédiaires utilisés dans la synthèse de ces antibiotiques.

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