Preparation of monacolin k

C - Chemistry – Metallurgy – 12 – P

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C12P 17/06 (2006.01) C07D 309/30 (2006.01)

Patent

CA 1129795

ABSTRACT "PREPARATION OF MONACOLIN K" Monacolin K,which is an antihypercholesteraemic agent of molecular formula C24H36O5, is prepared by cultivating one or more of the microorganisms Monascus anka SANK 10171 (IFO 6540), Monascus purpurous SANK 10271 (IFO 4513), Monascus ruber SANK 10671 (FERM 4958), Monascus vitreus SANK 10960 (FERM 4960), Monascus paxii SANK 11172 (IFO 8201) Monascus ruber SANK 13778 (FERM 4959), Monascus ruber SANK 15177 (FERM 4956) or Monascus ruber SANK 18174 FERM 4957) in a suitable culture medium and then isolating the Monacolin K from the resulting culture broth.

348220

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