Preparation of n-acyl alkylamines

C - Chemistry – Metallurgy – 07 – C

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C07C 231/18 (2006.01) C07C 211/27 (2006.01) C07C 233/02 (2006.01) C07C 271/08 (2006.01) C12P 13/00 (2006.01) C12P 41/00 (2006.01)

Patent

CA 2016913

T 658 FF ABSTRACT PREPARATION OF N-ACYL ALKYLAMINES N-Acyl-1-methyl-omega-phenylalkylamines predominantly in the form of the R enantiomer, are prepared by a process using a biocatalyst capable of stereoselectively hydrolysing the N-acyl group of the S enantiomer and recovering the remaining N-acyl-1-methyl-omega-phenylalkylamine predominantly in the form of the R enantiomer. The S enantiomer may be hydrolysed to yield the S enantiomer of the corresponding amine, which may be recovered. PS17002

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