Preparation of oligopeptide or amino acid alkyl ester.hcl salts

C - Chemistry – Metallurgy – 07 – K

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C07K 4/00 (2006.01) C07C 227/18 (2006.01) C07C 229/34 (2006.01) C07K 1/08 (2006.01) C07K 5/075 (2006.01)

Patent

CA 2085840

(10) PE 7032 A B S T R A C T The invention relates to a process for the preparation of an oligopeptide or amino acid alkyl ester.HCl salt, the alkyl group being methyl, ethyl, isopropyl or n- propyl, by converting an oligopeptide.HCl salt or amino acid.HCl salt with an alkanol corresponding to the alkyl group under the influence of an acid catalyst, 0.01-0.5 mol HCl relative to the oligopeptide.HCl salt or amino acid.HCl salt in combination with an acid ion exchange resin being used as acid catalyst.

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