Preparation of opiates, intermediates and uses of salts

C - Chemistry – Metallurgy – 07 – D

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C07D 489/02 (2006.01) C07D 489/04 (2006.01) C07D 489/08 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2241772

A process for the preparation of thebaine, its salts such as the bitartrate, and analogues thereof, together with a novel intermediate useful in said process are disclosed. Thebaine bitartrate is itself useful in the preparation of oxycodone; analogues are useful in the preparation of analogous 14-hydroxymorphinones.

Divulgation concernant une méthode pour préparer la thébaïne, ses sels, notamment le bitartrate, et ses analogues, de concert avec un nouvel intermédiaire utile dans ladite méthode. Le bitartrate de thébaïne est lui-même utile pour la préparation de l'oxycodone; les analogues peuvent servir pour la préparation de 14-hydroxymorphinones analogues.

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