C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 63/00 (2006.01) A61K 31/575 (2006.01) A61P 31/18 (2006.01) C07J 53/00 (2006.01)
Patent
CA 2633402
This invention relates to a novel process for making 3-O-(3',3'- dimethylsuccinyl)betulinic acid ("DSB")- This invention also relates to methods of treating HIV and related diseases using pharmaceutical compositions comprising salt forms of DSB prepared according to the process of the present invention. The invention further relates to dosage forms of pharmaceutical compositions comprising salts of DSB made using the process of this invention.
L'invention concerne un nouveau procédé de préparation d'acide 3-O-(3',3'-diméthylsuccinyl)bétulinique ("DSB"), ainsi que des procédés de traitement du VIH et de pathologies apparentées en utilisant des compositions pharmaceutiques qui comprennent des formes sels du DSB préparées suivant le procédé de la présente invention. L'invention concerne en outre des formes de doses de compositions pharmaceutiques comprenant des sels de DSB produits en utilisant le procédé de l'invention.
Hausherr Arndt
Hemp Christian
Nitz Theodore J.
Swaringen Roy
Goudreau Gage Dubuc
Panacos Pharmaceuticals Inc.
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