Preparation of pharmaceutically-active granules

Details Preparation of pharmaceutically-active granules Preparation of pharmaceutically-active granules

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 31/135 (2006.01) A61K 31/137 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2281420

The present invention provides a core of predominately microcrystalline cellulose, on which an active drug is layered onto the core via solution coating. The coated particles have a narrower particle size distribution than coated granules provided by other processes. An optional final coating of a pharmaceutically acceptable polymeric coating is provided to provide tastemaking or controlled release, and protection of the drug-layered particles.

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