Preparation of polymorphically pure terfenadine

Details Preparation of polymorphically pure terfenadine Preparation of polymorphically pure terfenadine

C - Chemistry, Metallurgy

07

D

260/292.2

C07D 211/22 (2006.01)

Patent

CA 1312610

ABSTRACT OF THE DISCLOSURE Polymorphically pure terfenadine, 1-(p-tert-butyl- phenyl)-4-[4'-(.alpha.-hydroxydiphenylmethyl)-1'-piperidinyl]- butanol, is prepared by carefully controlled recrystal- lization methods.

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