Preparation of polypeptides having human gamma enterferon...

Details Preparation of polypeptides having human gamma enterferon... Preparation of polypeptides having human gamma enterferon...

C - Chemistry, Metallurgy

12

N

195/1.14, 195/1.

C12N 15/23 (2006.01) C07K 14/57 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1339892

Partial sequences of human ~-interferon, comprising aminoacid sequences 5 to 127, 1 to 127 and 5 to 146, have biological activity. These partial sequences can be obtained by a genetic engineering process, for which purpose the appropriate DNA sequences are chemically synthesized. The DNA sequences are incorporated in hybrid plasmids, and the latter are introduced into host organisms and their expression is induced there. The biologically active polypeptides are suitable, as is human ~-interferon, for medicaments.

479511

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