Preparation of powder agglomerates

Details Preparation of powder agglomerates Preparation of powder agglomerates

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 31/167 (2006.01) A61K 31/573 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2706634

The invention relates to a method of producing an agglomerate of drug and solid binder. The process involves producing individual agglomerate particles and then converting the convertible amorphous content of same, following agglomeration, by the application of, for example, moisture. Agglomerates capable of conversion as well as the finished agglomerates and oral and nasal dosing systems including same are also contemplated. The process produces agglomerates which are rugged but which will produce an acceptable fine particle fraction during dosing.

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