C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
260/229
C07H 19/02 (2006.01) C07H 19/06 (2006.01) C07H 19/16 (2006.01) C07H 21/00 (2006.01)
Patent
CA 1189069
ABSTRACT OF THE DISCLOSURE 3'-deoxynucleosides are prepared from 2',5'-diprotected ribonucleosides by a process in which the 3'-hydroxy of the 2',5'-diprotected ribonucleoside is replaced with a substituted thiocarbonyl group, e.g. by reaction with phenylchlorothionocarbonate, and then reduced e.g. with tri(n-butyl)tin monohydride, to form the 3'-deoxy compound.
422144
Ogilvie Kelvin K.
Stewart & Kolash Ltd
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