C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 339/06 (2006.01)
Patent
CA 2729823
The invention provides .beta.-sulfonamide .alpha.-keto esters and amides in which the .alpha.-keto is protected as a 1,3-dithiolane derivative. Also provided are methods for preparing such esters and amides and for incorporating them into peptides.
La présente invention concerne des esters et amides de a-céto-ß-sulfonamide dans lesquels le a-céto est protégé sous la forme dun dérivé 1,3-dithiolane. La présente invention concerne en outre des procédés pour préparer de tels esters et amides et pour incorporer ceux-ci dans des peptides.
Forslund Raymond E.
Harrison Cristian L.
Ibrahim Shereen
Looker Adam R.
Martinot Theodore A.
Gowling Lafleur Henderson Llp
Vertex Pharmaceuticals Incorporated
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