C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/56 (2006.01) A61K 9/127 (2006.01) B01J 13/00 (2006.01) C07K 14/745 (2006.01) G01N 33/86 (2006.01)
Patent
CA 2097199
A prothrombin time reagent is disclosed for use in a prothrombin time test. The reagent utilizes recombinant human tissue factor, phospholipids of a natural or synthetic origin, a buffer composition and calcium ion. Stabilizers and salts may also be utilized in the reagent. In addition, a method for creating lipid micelles containing tissue factor is also disclosed.
L'invention concerne un réactif du temps de la prothrombine que l'on utilise dans un test du temps de la prothrombine. Le réactif utilise un facteur tissulaire humain de recombinaison, des phospholipides d'origine naturelle ou synthétique, une composition tampon et un ion calcium. Des stabilisateurs et des sels peuvent également être utilisés dans le réactif. De plus, une procédé de création de micelles lipides contenant le facteur tissulaire est également décrit.
Hawkins Pamela L.
Johnson Kevin B.
Maynard James
Tejidor Liliana
Baxter Diagnostics Inc.
Siemens Healthcare Diagnostics Inc.
Sim & Mcburney
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