Preparation of quinoline-substituted carbonate and carbamate...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 215/14 (2006.01) C07C 33/03 (2006.01) C07C 43/303 (2006.01) C07C 47/22 (2006.01) C07C 57/04 (2006.01) C07C 69/54 (2006.01) C07C 69/96 (2006.01) C07C 271/08 (2006.01) C07D 215/12 (2006.01)

Patent

CA 2719425

The invention relates to a process for preparing quinoline-substituted carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O- substituted marcolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or (II) or substrate that can be reduced to obtain the same.

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