Preparation of stable insulin analog crystals

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/62 (2006.01) A61K 38/28 (2006.01)

Patent

CA 2161495

The present invention discloses a process of preparing a crystalline alkali metal or ammonium salt of LysB28ProB29-human insulin. The process is useful in the purification and manufacture of LysB28ProB29-human insulin. LysB28ProB29-human insulin is useful in the treatment of diabetes.

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