C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/277.35
C07D 401/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 1292745
ABSTRACT OF THE DISCLOSURE: The invention relates to compounds of formula I Image ( I ) wherein X represents an oxygen or sulphur atom or a group of formula -NH-, -NAlk- (in which the substituent Alk represents a C1-6 alkyl group) or -NH-?-; and R1 and R2, which may be the same or different, each represents a hydrogen atom or a phenyl or naphthyl group or, together with the carbon atoms to which they are attached, represent a phenyl group, which phenyl group may optionally be substituted by a C1-6 alkyl, C1-6 alkoxy or C1-6 alkylthio group, by one or more halogen atoms, by a nitro group, by a trifluoromethyl group, or by a group of formula -CH2-?O-Alk (in which the substituent Alk represents a C1-6 alkyl group), and to pharmaceutically acceptable addition salts thereof. These compounds and their salts are useful in the treatment of allergic asthmatic conditions and bronchitis having allergic origin.
503171
Clements-Jewery Stephen
Kennewell Peter David
Westwood Robert
Robic
Roussel-Uclaf
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