Preparation of substituted ethenes

Details Preparation of substituted ethenes Preparation of substituted ethenes

C - Chemistry, Metallurgy

07

D

260/367.1, 260/3

C07D 307/52 (2006.01) C07C 319/20 (2006.01) C07C 319/22 (2006.01) C07C 323/27 (2006.01) C07D 317/58 (2006.01)

Patent

CA 2013841

A potassium salt useful in the production of N-substituted-1-alkylthio-2-nitroethenamines is produced by the reaction of the dipotassium salt of nitrodithio~acetic acid with certain straight chain alkylamines, thereby converting only one of the KS-groups to an alkylamine group. The resulting monopotassium salt may be alkylated to produce the required N-substituted-1-alkylthio compound which may be reacted with a suitable amine to produce the histamine H2-antagonist ranitidine.

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