Preparation of t-cell and t-cell membrane for use in...

A - Human Necessities – 61 – K

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A61K 35/18 (2006.01) A61K 35/14 (2006.01) A61K 35/26 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1328601

ABSTRACT OF THE DISCLOSURE Pharmaceutical preparations are provided for preventing or treating autoimmune diseases in which the active principle is activated T-lymphocyte cells, spe- cific for the autoimmune disease to be treated, which cells have been treated by incubation with a photoacti- vatable psoralen cross-linking agent, such as 8- methoxypsoralen, and then photoactivated. The active principle may also be the membrane fraction of such cells. Such preparations may be formulated into pharma- ceutical compositions and administered to prevent or treat autoimmune diseases.

593746

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