Preparation of toluoyl-5-pyrryl-2-acetonitrile

C - Chemistry – Metallurgy – 07 – D

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C07D 207/32 (2006.01) C07C 303/00 (2006.01) C07D 207/337 (2006.01)

Patent

CA 1040207

ABSTRACT OF THE DISCLOSURE A process for preparing a mixed anhydride acylating agent produced by reacting an aromatic acid selected from benzoic acid and p-toluic acid and an organo-substituted in- organic acid selected from methane sulfonic acid and toluene sulfonic acid and a process for acylating pyrrole derivatives such as 1-methylpyrrole-2-acetonitrile using the mixed anhydride acylating agent to prepare 5-aroylpyrrole-2- acetonitriles.

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