Preparation process for bioabsorbable polyester

Details Preparation process for bioabsorbable polyester Preparation process for bioabsorbable polyester

C - Chemistry, Metallurgy

08

G

402/201

C08G 63/08 (2006.01) A61K 9/20 (2006.01) A61L 17/12 (2006.01) A61L 31/06 (2006.01) C08G 63/90 (2006.01)

Patent

CA 2001710

A process is provided herein for the preparation of a bioabsorbable polyester having recurring structural units represented by the Formula (I): Image (I) wherein R1 and R2 are a hydrogen atom or a methyl group and can be the same or different, by the polymerization reaction of at least one of a glycolide and a lactide. In the described process the polyester is treated under reduced pressure in a reaction system, while maintaining the polyester in a molten state during the second half of the polymerization reaction can be the same or different. A polyester is obtained which contain almost no residue of unreacted monomers and volatile ingredients of low molecular weight.

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