Preparation process of difluoroacetophenone derivative

C - Chemistry – Metallurgy – 07 – C

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C07C 323/22 (2006.01) C07C 319/20 (2006.01)

Patent

CA 2296668

The invention relates to a process for preparing a difluoroacetophenone derivative (4) by alkylthionating a compound (1) into a compound (2) and reacting this compound with a compound (3). (see above formula) wherein X1 is Cl, Br or I, X2 and X3 are independently a halogen atom, H or perfluoroalkyl group, X4 is a halogen atom, R1 is an alkyl, aryl or aralkyl group, and R2 is methyl, ethyl or cyclopropyl group.

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