Preparation process of indoles

Details Preparation process of indoles Preparation process of indoles

C - Chemistry, Metallurgy

07

D

260/319.7

C07D 209/08 (2006.01) B01J 23/50 (2006.01) B01J 23/89 (2006.01) C07D 209/04 (2006.01)

Patent

CA 2029361

A process is provided for the preparation of an indole from aniline or a derivative thereof and a polyhydric alcohol. The reaction is carried out in the presence of a catalyst composed of a carrier having a specific surface area of at least 10 m/g and silver supported on the carrier. The catalyst also contains as an additional component a specific amount of at least one element selected from Co, Fe and Ni. Deterioration in catalytic performance of the catalyst during the reaction and its regeneration are therefore minimized.

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