Preparation process of n-formyl-.alpha.-aspartyl phenylalanine

C - Chemistry – Metallurgy – 07 – K

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530/5.06

C07K 5/06 (2006.01) C07K 5/075 (2006.01) C07K 11/02 (2006.01)

Patent

CA 1273749

Abstract of the Disclosure: This invention relates to an improved process for preparing N-formyl-.alpha.-aspartyl phenyl- alanine. More specifically, it relates to a process for preparing N-formyl-.alpha.-aspartyl phenylalanine by condensating N-formyl aspartic acid anhydride and phenylalanine which comprises effecting the condensa- tion reaction in a water medium while maintaining the pH during the reaction in the range of 7 - 12 and at a reaction temperature of 50°C or below.

497419

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