Preparation process of novel derivatives of 2-oxo- pyrid...

C - Chemistry – Metallurgy – 07 – D

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260/279, 260/279

C07D 401/04 (2006.01)

Patent

CA 1195333

PRECIS DE LA DIVULGATION: L'invention concerne la préparation des dérivés (I): Image (I) où R est hydrogène, alkyle (1-8c), aralkyle (7-12c); Z est hydrogène, CH3, alkyle ou hydroxyalkyle (2-8c), aryloxy- alkyle (7-12c), aralkyle (7-12c) éventuellement substitué par halogène, par alkoxy (1-4c), par alkyle (1-4c) ou par OH, CF3, OCF3, NO2 ou NH2, ou Z est cycloalkylalkyle (4-12c), alkényle ou alkynyle (3-8c) et a et b sont hydrogène ou forment une liaison carbone-carbone et de leurs sels avec les acides. Les dérivés (I) et leurs sels sont utiles comme médicaments, notamment stimulants dopaminergiques et anti- anoxiques.

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