Preparation process of novel substituted quinoleins

C - Chemistry – Metallurgy – 07 – D

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C07D 409/14 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) C07D 215/42 (2006.01) C07D 215/46 (2006.01) C07D 295/08 (2006.01) C07D 295/14 (2006.01) C07D 333/32 (2006.01) C07D 333/38 (2006.01) C07D 401/14 (2006.01) C07D 409/12 (2006.01) C07D 295/10 (2006.01)

Patent

CA 1093077

PRECIS DE LA DIVULGATION : L'invention a pour objet un procédé de pré- paration des nouvelles quinoléines substituées de formule I : Image (I) dans laquelle X en position 6, 7 ou 8 représente un atome d'hydrogène, un atome d'halogène, un groupement trifluoro- méthyle, et Y en position 2, 3 ou 4 représente un atome d'hydrogène, un atome d'halogène, un groupement trifluoro- méthyle, ainsi que des sels d'addition de ces composés avec les acides pharmaceutiquement acceptables. Lesdites quino- léines possèdent une remarquable activité analgésique.

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