Preparations for treatment of acne vulgaris

A - Human Necessities – 61 – K

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A61K 39/02 (2006.01) A61K 8/99 (2006.01) A61K 35/74 (2006.01) A61K 39/05 (2006.01)

Patent

CA 1052696

ABSTRACT OF THE DISCLOSURE Preparations for local treatment of acne vulgaris, particularly in the form of ointments or face lotions, are prepared by mixing with a suitable cosmetic medicine an active substance prepared by (a) growing Coryne bacteria acnes in a liquid growth medium until the multiplication peak is passed, (b) obtaining acnecine inhibitor discharged by said bacteria into the surrounding medium from the bacteria as an inhibitor-containing liquid, (c) concentrating said inhibitor-containing liquid into a liquid concentrate, and (d) incorporating said liquid concentrate in a water-in-oil emulsion by adding emulsifiers. In ointment form the prepara- tion normally contains about 20-40% of the liquid concentrate of step (d).

247098

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