Preparing biological samples for analysis

Details Preparing biological samples for analysis Preparing biological samples for analysis

G - Physics

01

N

G01N 1/44 (2006.01) G01N 33/48 (2006.01)

Patent

CA 2617968

Methods and devices for preparing a biological sample for analysis are described. The biological sample from an organism has at least macromolecule having a primary structure that naturally degrades after the sample is removed from the organism. The method includes causing the biological sample to adopt a shape to permit rapid and uniform heating. The shaped sample is then rapidly and uniformly heated, thereby altering a secondary structure of the macromolecule while preserving its primary structure.

Cette invention concerne des méthodes et des dispositifs de préparation d'échantillons biologiques aux fins d'analyse. L'échantillon biologique prélevé sur un organisme compte au moins une macromolécule présentant une structure primaire qui se dégrade naturellement après prélèvement. La méthode consiste à faire adopter à l'échantillon biologique une forme permettant de le chauffer rapidement et uniformément. L'échantillon ainsi façonné est alors chauffé rapidement et uniformément, ce qui modifie une structure secondaire de la macromolécule tout en conservant la structure primaire.

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