Preservation of blood platelets

A - Human Necessities – 01 – N

Patent

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A01N 1/02 (2006.01) A61K 35/14 (2006.01)

Patent

CA 2156433

Methods and compositions for preserving plateletes at cryogenic temperatures with retention of hemostatic activity are provided. The compositions include a first agent for inhibiting actin filament severing and a second agent for inhibiting actin polymerization. Contacting the platelets with the first and second agents prior to exposure to cold temperature prevents cold-induced platelet activation.

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