Pretargeting methods and compounds

Details Pretargeting methods and compounds Pretargeting methods and compounds

C - Chemistry, Metallurgy

07

K

C07K 14/765 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/04 (2006.01) A61K 51/12 (2006.01) C07D 495/04 (2006.01) C07F 9/547 (2006.01) C07H 7/02 (2006.01) A61K 43/00 (1990.01)

Patent

CA 2134239

Methods, compounds, compositions and kits that relate to pretargeted delivery of diagnostic and therapeutic agents are disclosed. In particular, methods for radiometal labeling of biotin and for improved radiohalogenation of biotin, as well as related compounds, are described. Also, clearing agents, anti-ligand-targeting moiety conjugates, target cell retention enhancing moieties and additional methods are discussed.

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