Pretargeting methods and compounds

Details Pretargeting methods and compounds Pretargeting methods and compounds

C - Chemistry, Metallurgy

07

K

C07K 16/00 (2006.01) A61K 31/70 (2006.01) A61K 47/26 (2006.01) A61K 47/36 (2006.01) A61K 47/48 (2006.01) C07D 495/04 (2006.01) C07H 15/14 (2006.01)

Patent

CA 2178477

Methods, compounds, compositions and kits that relate to pretargeted delivery of diagnostic and therapeutic and therapeutic agents are disclosed. In particular, methods for radiometal labeling of biotin, as well as related compounds, are described. Clearing agents and clearance mechanisms are also discussed.

L'invention concerne des procédés, composés, compositions et trousses permettant l'apport préalablement ciblé d'agents diagnostiques et thérapeutiques. Cette invention se rapporte en particulier à des procédés permettant un marquage radiométallique de la biotine, ainsi qu'à des composés associés. Sont également décrits des agents et des mécanismes de clairance.

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