Preventing and treating elevated intraocular pressure...

A - Human Necessities – 61 – K

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A61K 31/405 (2006.01) A61K 31/19 (2006.01) A61K 31/195 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2177578

Methods and compositions for preventing or treating non-inflammatory elevated intraocular pressure associated with administered or endogenous steroids including administering to a mammalian organism a composition including (a) an ophthalmologically effective amount of non-steroidal cyclooxygenase inhibitor, and (b) a pharmaceutically acceptable carrier, to reduce or prevent an elevation of intraocular pressure and/or protein marker induction induced by chronic exposure to glucocorticoids.

Méthodes et compositions de prévention et de traitement des pressions intraoculaires élevées à caractère non inflammatoire associées à des stéroïdes administrés ou endogènes consistant à administrer à un mammifère une préparation contenant (a) une dose à efficacité ophtalmologique d'un inhibiteur non stéroïde de la cyclooxygénase et (b) un excipient pharmacocompatible, pour réduire ou prévenir l'élévation de la pression intraoculaire et/ou l'induction de marqueurs de protéines due à une exposition chronique aux glucocorticoïdes.

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