Preventing or treating epithelial tissue damage or hair loss

Details Preventing or treating epithelial tissue damage or hair loss Preventing or treating epithelial tissue damage or hair loss

A - Human Necessities

61

K

A61K 31/00 (2006.01) A61K 8/30 (2006.01) A61P 17/00 (2006.01) A61P 17/14 (2006.01) A61Q 7/00 (2006.01)

Patent

CA 2496453

The present invention pertains to a method for preventing and/or treating epithelial tissue damage, such as is effected by inflammatory reactions, ageing or cancer and/or to prevent and/or treat hair loss. In particular, the present invention relates to substances and/or compositions modifying, in particular blocking endogenous CD1d function. According to another aspect the present invention also provides a method for screening for compounds suitable for use in the method and the composition of the present invention.

La présente invention concerne une méthode permettant de prévenir et/ou de traiter une lésion de l'épithélium, due à des réactions inflammatoires, au vieillissement ou au cancer et/ou permettant de prévenir et/ou de traiter la perte des cheveux. La présente invention concerne notamment des substances et/ou des compositions modifiant, bloquant en particulier la fonction de la CD¿1d? endogène. Selon un autre aspect, la présente invention concerne également une méthode de criblage de composés pouvant être utilisés dans la méthode et dans la composition de la présente invention.

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