Prevention and reduction of blood loss

A - Human Necessities – 61 – K

Patent

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A61K 38/55 (2006.01) A61K 9/00 (2006.01) A61P 7/00 (2006.01)

Patent

CA 2488558

Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g., coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.

L'invention concerne des méthodes destinées à prévenir ou réduire l'ischémie et/ou une réaction inflammatoire systématique chez un patient, telle que la perte sanguine péri-opératoire et/ou une réaction inflammatoire systématique chez un patient soumis à une opération cardiothoracique, par exemple un pontage aortocoronarien ou autres interventions chirurgicales, en particulier lorsque de telles interventions impliquent une circulation extracorporelle comme le pontage cardiopulmonaire.

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