Prevention and reversal of chemotherapy-induced peripheral...

A - Human Necessities – 61 – K

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A61K 31/352 (2006.01) A61K 31/05 (2006.01) A61K 31/353 (2006.01) A61P 25/02 (2006.01)

Patent

CA 2668008

Provided herein are methods for treating or preventing neuropathy, neuropathy-related conditions, wherein the neuropathy or neuropathy-related conditions are induced by, or otherwise associated with, treatment of the subject with at least one chemotherapeutic agent, the methods comprising administering an effective amount of an isoflavonoid compound of formula (I). Also provided are methods for the treatment of nerve damage. Also provided are uses of isoflavonoid compounds of formula (I) in the treatment of neuropathy, neuropathy-related conditions and nerve damage.

L'invention concerne des procédés visant à traiter ou prévenir la neuropathie et les états associés à la neuropathie, la neuropathie ou les états associés à la neuropathie étant induits par ou associés au traitement du sujet avec au moins un agent chimiothérapeutique, les procédés comprenant l'administration d'une quantité efficace d'un isoflavonoïde de formule (I). L'invention concerne également des procédés visant à traiter l'endommagement des nerfs, et l'utilisation d'isoflavonoïdes de formule (I) dans le traitement de la neuropathie, des états associés à la neuropathie et de l'endommagement des nerfs.

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