Prevention and treatment of cerebral amyloid angiopathy

Details Prevention and treatment of cerebral amyloid angiopathy Prevention and treatment of cerebral amyloid angiopathy

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61P 9/00 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2684323

The invention provides improved agents and methods for treatment of cerebral amyloid angiopathy (CAA) and methods to effect prophylaxis of CAA. The methods can treat CAA concurrently with Alzheimer's disease or separately. The methods can effect prophylaxis of CAA concurrently with Alzheimer's disease or separately. The methods involve administering antibody that is specific for the N-terminus of Aß or an agent that can induce such an antibody.

L'invention concerne des agents améliorés et des procédés de traitement d'angiopathie amyloïde cérébrale (CAA) et des procédés pour effectuer une prophylaxie de CAA. Les procédés peuvent traiter CAA en même temps que la maladie d'Alzheimer ou de manière séparée. Les procédés peuvent effectuer la prophylaxie de CAA en même temps que la maladie d'Alzheimer ou de manière séparée. Les procédés nécessitent l'administration d'un anticorps qui est spécifique pour la terminaison N d'Ab ou d'un agent qui peut induire un tel anticorps.

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